K224 / K225 / 2027

Lesson 2 of 5 / Respiration in humans

Exchange gases at an alveolus

How do very small air spaces provide fast gas exchange?

I can link alveolar structure and blood supply to efficient diffusion.

  • I can identify named airways, alveoli and associated capillaries and their functions.Syllabus

    Syllabus K224 / K225, Topic 6(a). Identify named airways, alveoli and associated capillaries and their functions.

  • I can explain alveolar adaptations for gas exchange.Syllabus

    Syllabus K224 / K225, Topic 6(b). Explain alveolar adaptations for gas exchange.

About 5 min

Make a guess. You are not marked.

Oxygen passes from alveolar air into your blood. What moves it across?

  1. The heart pumps it into the blood.
  2. Active transport using energy from the lungs.
  3. Diffusion down a concentration gradient.
Show the answer

Diffusion down a concentration gradient.

Alveolar air has more oxygen than the blood arriving. Oxygen diffuses across the thin walls; no pump is needed.

The key idea

A large total surface area, thin moist walls and maintained gradients make alveoli effective exchange surfaces.

Follow one gas
oxygen diffuses from alveolar air to capillary bloodAlveolar airMoist inner surfaceBlood inBlood outCapillary bloodThin adjacent walls shorten the distance
Oxygen has a net movement from alveolar air into blood. Ventilation replenishes alveolar oxygen; blood flow carries oxygen away.

The two gases exchange at the same time in opposite net directions. The diagram isolates one arrow; it does not imply one-way motion of every molecule. Walls and gaps are enlarged for visibility.

Explanation

The wall of each alveolus is very thin, and so is the wall of the capillary next to it. So gases only have a short distance to travel between air and blood. The inside of the alveolus is moist, so gases dissolve before they cross.

There are millions of alveoli. Together they give a very large surface area, so a lot of gas can cross at the same time.

Blood arriving at the lungs has less oxygen than the air in the alveoli, so oxygen diffuses into the blood. It enters red blood cells and joins with haemoglobin. The blood has more carbon dioxide than the air in the alveoli, so carbon dioxide diffuses the other way, into the alveoli.

Breathing brings fresh oxygen into the alveoli and removes carbon dioxide. Blood flow brings new low-oxygen blood and takes oxygen-rich blood away. Together, they keep the concentration gradients steep, so diffusion keeps going.

Neither gas is pumped across. Both cross by diffusion, down their concentration gradients.

Step by step
  1. 1

    Pick a feature

    Choose one: a large surface area, thin walls, a moist lining or many capillaries close by.

  2. 2

    Say what it does

    Link the feature to more area, a shorter distance, gases dissolving, or a steep difference in concentration.

  3. 3

    Name the gas and the way it goes

    Oxygen goes into the blood. Carbon dioxide comes out of the blood.

Worked example

Damage to alveolar walls

Some walls separating neighbouring alveoli are destroyed. Explain why gas exchange can become less effective.

One way to explain it

Destroying walls reduces the total surface area available for diffusion. Less oxygen can cross into blood in a given time under otherwise comparable conditions, reducing oxygen delivery to body cells.

Why this answer works
  • Fewer walls means less exchange area, even if the remaining air spaces are larger.
  • State the effect on the rate of diffusion.
  • Link the change to oxygen delivery rather than simply saying the lung is weaker.

Watch out for this

A student says: "The capillary wall must be thick to keep air from leaking into blood." What is wrong with this?

Show the answer

Thin alveolar and capillary walls permit rapid diffusion of dissolved gases. Blood and alveolar air remain in separate spaces.

Check your understanding

Why does a continuous capillary blood supply help alveolar gas exchange?

  1. It brings oxygen-poor blood and removes oxygen-rich blood, maintaining a gradient.
  2. It makes the alveolar wall thicker.
  3. It carries inhaled air directly to the heart, which pumps the oxygen round the body.
Show the answer

It brings oxygen-poor blood and removes oxygen-rich blood, maintaining a gradient.

Maintaining the difference between alveolar air and incoming blood supports continued net oxygen diffusion.

Quick recall

Card 1 of 3. Answer in your head, then check.

How do very small air spaces provide fast gas exchange?

You can return to this lesson any time.